Cell Lines and Cell Cultures
ATCC SK-ES-1; Ewing's Sarcoma; Human (Homo sapiens)
SK-ES-1 is a cell line exhibiting epithelial morphology that was isolated from the bones of an 18-year-old, White male patient with anaplastic osteosarcoma. This product has applications in cancer research.
Eurofins Discoverx InCELL Hunter HEK 293 BLK Kinase Binding Cell Line, 2 vials. (96-0044C1)
The InCELL Hunter HEK 293 BLK Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of BLK via detection of BLK levels. This product uses EFC technology. The cell line included overexpresses BLK target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Enterobacter cloacae; Strain CDC 442-68; genomic DNA
Genomic DNA isolated from Enterobacter cloacae subsp. cloacae strain CDC 279-56 (ATCC 13047). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
Lonza Walkersville NHBE – Human Bronchial/Tracheal Epithelial Cells with Retinoic Acid
Normal and Diseased Bronchial Epithelial (NHBE and DHBE) cells are isolated from epithelial lining of airways above bifurcation of the lungs. Lonza's Normal Human Bronchial Epithelial Cells (NHBE) are available with retinoic acid. All Cryopreserved human bronchial epithelial cells are guaranteed through 15 population doublings. Cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.Benefits:All cells test negative for mycoplasma, bacteria, yeast, and fungiHIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lotsCertificate of Analysis provided for every cell lot Content:1 x Cryopreserved ampule NHBE w/ RA containing ≥500,000 cells
Amsbio LLC eLuCidate™ HEK 293T, RIG-I Reporter Cell Line
eLuCidate™ HEK 293T RIG-I Reporter Cell Line
Biochain Institute Inc Frozen Tissue Section - Human Tumor: Liver, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Innovative Research Inc Pooled Human Saliva 5ml
Pooled Human Saliva from Innovative Research is collected fresh from two or more donors, pooled, and stored frozen. Produced in the salivary glands, human saliva is 99.5% water, but contains many important substances including electrolytes, mucus, antibacterial compounds, and various enzymes.
ABclonal Technology ADORA2A Rabbit pAb
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily, specifically an A2A adenosine receptor. It responds to adenosine, activating G(s) and G(olf) proteins to increase intracellular cAMP levels. The receptor plays key roles in regulating cardiac rhythm, circulation, cerebral and renal blood flow, immune function, pain, and sleep. It is involved in conditions like inflammatory diseases and neurodegenerative disorders. Alternative splicing produces multiple transcript variants, including a read-through transcript with the upstream SPECC1L gene, thought to be non-coding.
ATCC D-17; Osteosarcoma; Dog (Canis familiaris)
D-17 is a cell line exhibiting epithelial morphology that was isolated in 1969 derived from an osteosarcoma metastatic to the lung in an 11-year-old, female poodle. This cell line was deposited by WA Nelson-Rees.
Eurofins Discoverx Ready-to-Assay 5-HT2B Serotonin Receptor Frozen Cells, 2 Vials of Cells. (HTS109RTA)
The Ready-to-Assay 5-HT2B Serotonin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. serotonin/5-HT) based activation of HTR2B GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR2B alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of HTR2B, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC HT-3; Cervical Carcinoma; Human (Homo sapiens)
HT-3 is an epithelial-like cell that was isolated from the lymph node of a 58-year-old, White, female with cervical carcinoma. The cell line can be used in cancer research.
ATCC Mycoplasma hominis; Quantitative CRM; genomic DNA
Quantified genomic DNA isolated from Mycoplasma hominis strain [LBD-4] (ATCC 27545). This quantitative external control was produced under an ISO 17034 accredited process for use in testing and calibration in ISO 17025 accredited laboratories, inclusivity/exclusivity testing, establishing limits of detection, verification or comparison of test methods, and other molecular applications.
Eurofins Discoverx PathHunter CHO-K1 MR Nuclear Translocation Cell Line, 2 vials. (93-0451C2)
The PathHunter MR Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. aldosterone) based NHR activation via detection of resulting MR (mineralocorticoid receptor) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged MR NHR and nuclear localized EA. Upon activation of MR, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
ATCC Keister's Modified TYI-S-33 Medium 1 vial prepares 15ml of medium
Keister's Modified TYI-S-33 Giardia Medium [ATCC Medium 2695] is the recommended formulation for the axenic cultivation of Giardia and Spironucleus. It is provided freeze-dried, complete with 10% bovine serum, 1 vial prepares 15 mL of medium.
ATCC Escherichia coli
Escherichia coli strain K-12 was isolated from the feces of a diphtheria convalescent. This whole-genome sequenced strain carries F1 and phage lambda (F+ lambda+) and is known to be lytic on Escherichia coli strain W1485 (ATCC 12435).